Description
Cimetidine Tablets
Healthy Inc is a specialized global supplier and exporter of established gastrointestinal therapeutics. We provide high-purity Cimetidine Tablets, sourced from WHO–GMP certified solid dosage facilities. This “First-Generation” H2 Antagonist is a top export to pharmacy chains, government health tenders, and veteran care clinics in Africa, LATAM, and Southeast Asia, recognized historically as the breakthrough drug for the non-surgical management of peptic ulcers.
Product Overview
This formulation contains Cimetidine, the prototype histamine H2-receptor antagonist.
The “Ulcer Healing” Pioneer:
- Mechanism: Cimetidine competitively inhibits the action of histamine at the H2-receptors of the parietal cells in the stomach. By blocking this pathway, it significantly reduces both the volume and the acidity of gastric juice (hydrochloric acid).
- Basal Acid Suppression: It is particularly effective at inhibiting nocturnal (nighttime) basal acid secretion, which is crucial for allowing duodenal ulcers to heal while the patient sleeps.
- Immune Modulation: Uniquely, Cimetidine also blocks H2 receptors on T-suppressor cells, occasionally used off-label for immune enhancement (e.g., treating warts or adjunct in certain cancers).
Product Composition & Strength
We supply this product as Film Coated Tablets (Green or Blue). The coating masks the characteristic bitter taste and sulfur-like odor of the drug.
| Active Ingredient | Strength (Standard) | Primary Role |
|---|---|---|
| Cimetidine USP/BP | 200 mg | Prophylaxis / Maintenance |
| Cimetidine USP/BP | 400 mg | Standard Therapeutic Dose |
| Cimetidine USP/BP | 800 mg | Once-Daily (Bedtime) |
| Excipients | Q.S. | Povidone / Magnesium Stearate |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 100s, or Bulk HDPE Jars of 500s/1000s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Film Coated Tablet (Oral) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister |
| Storage | Store below 30°C. Protect from light. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Polymorph Control: Cimetidine exhibits polymorphism (forms A, B, and C). Form A is the most thermodynamically stable and bioavailable. We strictly control our API supply chain and crystallization process to ensure only Form A is present in the final dosage form.
- Odor Masking: The drug has a mild mercaptan (sulfur) odor. Our film-coating process creates a hermetic barrier that locks in the odor, ensuring the product is acceptable to patients.
Therapeutic Indications (Human Use)
Indicated for the short-term treatment and maintenance of:
- Duodenal Ulcer: Active treatment and prevention of relapse.
- Benign Gastric Ulcer: Short-term treatment.
- GERD: Treatment of erosive gastroesophageal reflux disease.
- Pathological Hypersecretory Conditions: Zollinger-Ellison Syndrome (often requires high doses).
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Duodenal Ulcer: 800 mg once daily at bedtime OR 400 mg twice daily (morning and bedtime). Treatment usually lasts 4–6 weeks.
- Benign Gastric Ulcer: 800 mg once daily at bedtime.
- GERD: 400 mg four times daily (with meals and at bedtime).
- Renal Impairment: Dosage must be reduced in patients with kidney failure (e.g., 300 mg every 12 hours) to avoid accumulation and CNS toxicity.
Safety Warnings:
- Drug Interactions (CYP450 Inhibitor – CRITICAL): Cimetidine is a potent inhibitor of cytochrome P450 enzymes. It slows the metabolism of Warfarin, Phenytoin, Theophylline, and Lidocaine, leading to toxic levels of these drugs. Dosage adjustments are mandatory.
- Anti-Androgenic Effects: High doses or long-term use can cause gynecomastia (breast enlargement) and impotence in men due to displacement of dihydrotestosterone.
- CNS Effects: Confusion and hallucinations may occur, especially in the elderly or those with renal impairment.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
