Description
Nitroglycerin (Glyceryl Trinitrate) Sublingual Tablets (0.4 mg / 0.5 mg)
Healthy Inc is a premier global provider of emergency cardiovascular interventions. We provide premium Nitroglycerin Sublingual Tablets, manufactured in WHO–GMP certified specialized high-potency suites. As the gold-standard frontline treatment for acute angina pectoris, this product is a critical export for cardiac ambulance services, emergency departments, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the Middle East.
Product Overview
Nitroglycerin (GTN) is a potent organic nitrate vasodilator. Formulated specifically for sublingual administration, it bypasses the “first-pass” hepatic metabolism, allowing the medication to enter the systemic circulation directly via the sublingual mucosa for near-instantaneous cardiac relief.
The “Life-Saving Vasodilator” Specialist:
- Mechanism of Action: Nitroglycerin is converted into Nitric Oxide (NO) within the vascular smooth muscle. NO activates guanylate cyclase, increasing cGMP levels, which leads to powerful venous and arterial vasodilation. This reduces myocardial oxygen demand by decreasing both preload and afterload.
- Rapid Onset of Action: Therapeutic effects typically begin within 1 to 3 minutes of administration, making it indispensable for the management of acute anginal attacks and suspected myocardial ischemia.
- Hemodynamic Precision: By dilating the coronary arteries, it redistributes blood flow to ischemic subendocardial regions, effectively resolving “chest pressure” and pain.
Technical & Manufacturing Specifications
Formulated for rapid disintegration and high chemical stability.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Nitroglycerin (Diluted) BP / USP / IP |
| Dosage Form | Sublingual Tablets |
| Available Strengths | 0.4 mg (400 mcg), 0.5 mg (500 mcg) |
| HS Code | 3004.90.79 (Vasodilators) / 2920.90.00 |
| Packaging | Amber Glass Vials or specialized Alu-Alu Blister |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- Volatility Management: Nitroglycerin is highly volatile. Our manufacturing utilizes specialized stabilizers and non-porous excipients to prevent the “migration” of the active ingredient between tablets, ensuring dose consistency.
- Rapid Disintegration (Sublingual): Our tablets are engineered to dissolve in less than 30 seconds under the tongue, a critical parameter for emergency efficacy.
- Environmental Protection: To prevent degradation from light and moisture, we utilize Amber Glass packaging with tight-sealing caps, preserving potency for 24 months even in tropical export markets.
Therapeutic Indications & Clinical Symptoms
- Acute Angina Pectoris: Immediate relief of chest pain caused by coronary artery disease.
- Prophylaxis: Taken 5-10 minutes before physical activities known to trigger anginal episodes.
- Acute Heart Failure: Used in emergency settings to reduce pulmonary congestion and cardiac workload.
Dosage & Administration
- Emergency Use: Dissolve one tablet under the tongue at the first sign of an attack. May be repeated every 5 minutes (up to 3 doses).
- Important Instruction: Do not swallow the tablet. Sit down before taking to avoid dizziness caused by rapid blood pressure drops.
- Safety Note: Absolute Contraindication with Sildenafil or other PDE5 inhibitors (causes life-threatening hypotension). Common side effects include “Nitrate Headache” and orthostatic hypotension.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Cardiovascular Exporter in Mumbai, catering to Emergency Medical Services and Government Health Tenders. We offer Third Party Manufacturing for Nitroglycerin Tablets with full Dossier support. Our logistics network ensures secure transit to Vietnam, Nigeria, UAE, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
Commercial Inquiries
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
