Description
Metformin Hydrochloride (SR) & Glimepiride Tablets
Healthy Inc is a specialized global supplier and exporter of advanced anti-diabetic fixed-dose combinations. We provide high-quality Metformin Hydrochloride (Sustained Release) & Glimepiride Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Dual-Action” metabolic regulator is a top export to chronic care clinics, pharmacy chains, and diabetic associations in Africa, LATAM, and Southeast Asia, serving as a cornerstone therapy for managing uncontrolled Type 2 Diabetes Mellitus.
Product Overview
This formulation combines Metformin Hydrochloride (a Biguanide sensitizer) in a Sustained Release matrix with Glimepiride (a 3rd Generation Sulfonylurea secretagogue).
The “Total Glycemic Control” Specialist:
- Dual Mechanism: Glimepiride stimulates the pancreas to release more insulin, while Metformin decreases glucose production in the liver and improves insulin sensitivity in muscle tissues.
- Sustained Release (SR) Technology: The Metformin component is formulated as a Sustained Release matrix, ensuring steady blood levels over 24 hours, reducing gastrointestinal side effects, and improving patient compliance with once or twice-daily dosing.
- Synergistic Effect: More effective in lowering HbA1c levels than either agent used alone.
- Cardiovascular Safety: Glimepiride binds to a different receptor site than older sulfonylureas, preserving the heart’s ischemic preconditioning response.
Product Composition & Strength
We supply this product in Bilayer Tablets or Matrix Tablets packed in Alu-Alu or PVC/PVDC Blisters.
| Product Strength | Metformin HCl (SR) | Glimepiride | Common Name |
|---|---|---|---|
| 500/1 mg | 500 mg | 1 mg | G1 Tablet |
| 500/2 mg | 500 mg | 2 mg | G2 Tablet |
| 1000/2 mg | 1000 mg | 2 mg | Forte / DS Tablet |
| 1000/4 mg | 1000 mg | 4 mg | High Strength |
*Pack Sizes: Blister packs of 10s, 15s, or 30s (Box of 10×10 or 10×15).
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Bilayer / Film Coated Tablet (Oral) |
| Packaging | Alu-Alu Blister (Moisture Sensitive) |
| Storage | Store below 25°C. Protect from moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate, CTD Dossier |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Bilayer Technology: Our manufacturing process often utilizes bilayer compression to physically separate the Glimepiride and Metformin layers, preventing chemical interaction and ensuring the stability of both APIs.
- Dissolution Profile: Rigorously tested to ensure the “SR” component releases drug consistently over 10-12 hours, preventing dose dumping.
Therapeutic Indications (Human Use)
Indicated for the management of Type 2 Diabetes Mellitus:
- Second-Line Therapy: When diet, exercise, and single-agent therapy (Metformin or Glimepiride alone) do not result in adequate glycemic control.
- Replacement Therapy: For patients already stabilized on separate tablets of Metformin and Glimepiride, offering convenience in a single pill.
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Timing: Should be taken once or twice daily with meals (usually breakfast or the first main meal) to reduce GI upset and risk of hypoglycemia.
- Titration: Dose must be titrated based on blood glucose monitoring and HbA1c targets.
- Swallowing: Tablets must be swallowed whole; do not crush or chew the SR formulation.
Safety Warnings:
- Hypoglycemia: Contains a Sulfonylurea (Glimepiride), which can cause low blood sugar if a meal is skipped or after heavy exercise.
- Lactic Acidosis: Rare but serious risk linked to Metformin accumulation, especially in patients with renal impairment or dehydration.
- Alcohol Warning: Avoid excessive alcohol intake as it potentiates the risk of both hypoglycemia and lactic acidosis.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
