Atenolol & Chlorthalidone Tablets

Healthy Inc is a specialized global supplier and exporter of combination cardiovascular therapies for long-term hypertension management. We provide high-stability Atenolol & Chlorthalidone Tablets, sourced from WHO–GMP certified solid dosage facilities. This synergistic “Beta-Blocker & Diuretic” combination is a primary export to cardiology clinics, community health centers, and government hospital tenders in Africa, LATAM, and Southeast Asia, specifically indicated for patients who require multi-pathway blood pressure control.

Product Overview

This formulation combines a cardioselective beta-1 adrenergic receptor blocker with a long-acting monosulfonamyl diuretic to achieve superior systemic pressure reduction through volume depletion and cardiac output modulation.

The “Cardiac & Volume” Specialist:

• Atenolol (The Beta-Blocker): A cardioselective Beta-1 receptor antagonist. It works by reducing the heart rate and force of contraction, thereby lowering cardiac output. It also inhibits the release of renin by the kidneys, further assisting in blood pressure reduction.
• Chlorthalidone (The Diuretic): A thiazide-like diuretic that inhibits sodium and chloride reabsorption in the distal convoluted tubule of the nephron. By increasing the excretion of sodium and water, it reduces plasma volume and extracellular fluid volume, leading to a decrease in peripheral vascular resistance.
• Synergy: The combination is more effective than either component used alone. The diuretic effect of Chlorthalidone can sometimes trigger a compensatory increase in heart rate (reflex tachycardia), which is effectively neutralized by the heart-rate-lowering effect of Atenolol.

Product Composition & Strength

We supply this product as Film Coated Tablets. The combination is engineered to maintain therapeutic plasma levels over a 24-hour period, supporting once-daily dosing.

*Standard FDC strengths: 50/12.5mg, 50/25mg, and 100/25mg.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Micronization Standards: Chlorthalidone has low aqueous solubility. Our manufacturing process involves advanced micronization of the API to ensure uniform distribution and consistent dissolution profiles across different batches.
• Photostability: Atenolol is sensitive to light. Our tablets feature an opaque film coating to ensure chemical stability throughout the product’s shelf life, even in transparent blister configurations.

Therapeutic Indications (Human Use)

Indicated for the treatment of hypertension:

• Essential Hypertension: Specifically where monotherapy has failed or where combination therapy is appropriate as initial treatment.
• Edema-associated Hypertension: Particularly useful for patients who show signs of fluid retention alongside high blood pressure.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Oral.
• Standard Dose: One tablet once daily.
• Administration: Best taken in the morning. Taking it later in the day may lead to increased nocturnal urination (nocturia) due to the diuretic component.

Safety Warnings:

• Bradycardia: Monitor heart rate; Atenolol may cause excessively slow heart rate.
• Electrolyte Imbalance: Chlorthalidone may cause low potassium (hypokalemia) or low sodium. Periodic electrolyte monitoring is advised.
• Abrupt Withdrawal: WARNING: Do not stop taking this medication suddenly. Rapid discontinuation of Beta-Blockers can cause severe rebound hypertension or cardiac events.
• Asthma/COPD: Use with caution in patients with reactive airway diseases.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.

Commercial Inquiries

For hospital tenders, bulk export, or distributor pricing, please contact our export team.

WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in