Sertraline Hydrochloride Tablets (25 mg / 500 mg / 100 mg)

Healthy Inc is a premier global supplier of high-stability neuropsychiatric therapies. We provide premium Sertraline Hydrochloride Tablets, manufactured in WHO–GMP certified psychiatric formulation units. As a frontline Selective Serotonin Reuptake Inhibitor (SSRI), this product is a vital export for mental health institutions, psychiatric clinics, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and Europe.

Product Overview

Sertraline is a potent and selective inhibitor of neuronal serotonin reuptake. It is specifically engineered to treat a broad spectrum of mood and anxiety disorders by enhancing serotonergic neurotransmission without significant affinity for adrenergic, dopaminergic, or histaminergic receptors.

The “Neuro-Balance” Specialist:

• Mechanism of Action: Sertraline blocks the serotonin transporter (SERT) protein in the presynaptic terminal. By inhibiting the reuptake of serotonin (5-HT), it increases the concentration of the neurotransmitter in the synaptic cleft, facilitating long-term neuroplasticity and mood regulation.
• Superior Safety Profile: Compared to older tricyclic antidepressants, Sertraline has a minimal effect on cardiac conduction and a lower risk of sedation, making it suitable for elderly patients and those with comorbid medical conditions.
• Dopaminergic Synergy: Unique among SSRIs, Sertraline exhibits a weak inhibition of dopamine reuptake, which may contribute to its efficacy in treating lethargic depression and cognitive dysfunction.

Technical & Manufacturing Specifications

Formulated for precise impurity control and high molecular stability.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.

• Polymorph Control: Sertraline can exist in multiple crystalline forms (Polymorphs). Our manufacturing process ensures the exclusive use of Form II, the most stable and bioavailable polymorph, to ensure consistent drug release.
• Dissolution Velocity: Engineered for rapid disintegration, ensuring that the active pharmaceutical ingredient (API) reaches peak plasma concentration ($T_{max}$) consistently between 4.5 to 8 hours post-administration.
• High-Containment Standards: Produced in dedicated psychotropic blocks to prevent cross-contamination, ensuring the highest chemical purity and safety for long-term therapeutic use.

Therapeutic Indications & Clinical Symptoms

• Major Depressive Disorder (MDD): Treatment of acute episodes and prevention of relapse.
• Obsessive-Compulsive Disorder (OCD): Management of intrusive thoughts and repetitive behaviors in adults and pediatric patients.
• Panic Disorder: Reduction in the frequency of panic attacks with or without agoraphobia.
• Social Anxiety Disorder & PTSD: Treatment of chronic anxiety and post-traumatic stress symptoms.
• PMDD: Relief of physical and emotional symptoms associated with Premenstrual Dysphoric Disorder.

Dosage & Administration

• Titration: Usually started at 25 mg or 50 mg once daily, with gradual increments based on clinical response up to a maximum of 200 mg.
• Administration: Can be taken with or without food; morning or evening administration is acceptable.
• Safety Note: Patients should be monitored for “Serotonin Syndrome” when used in combination with other serotonergic agents. Gradual tapering is required to avoid withdrawal symptoms.

Global Export & Contract Manufacturing Services

Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to Institutional Wholesalers and NGO Mental Health Programs. We offer Third Party Manufacturing for Sertraline with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, Russia, and the Philippines, providing WHO-GMP quality at competitive B2B prices.

Commercial Inquiries

WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in