Description
Carbimazole Tablets (5 mg / 10 mg / 20 mg)
Healthy Inc is a premier global supplier of high-precision endocrine therapies. We provide premium Carbimazole Tablets, manufactured in WHO–GMP certified specialized hormone containment units. As a frontline treatment for hyperthyroidism and Graves’ disease, this product is a vital export for endocrinology clinics, metabolic health programs, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the Middle East.
Product Overview
Carbimazole is a thioamide antithyroid agent and a prodrug. Upon ingestion, it is rapidly and virtually completely converted to its active form, Methimazole. It is specifically engineered to decrease the production of thyroid hormones, providing a controlled clinical path to euthyroidism.
The “Thyroid Regulator” Specialist:
- Mechanism of Action: Carbimazole inhibits the enzyme thyroid peroxidase (TPO). This prevents the iodination of tyrosine residues on thyroglobulin and the subsequent coupling of iodotyrosines, effectively blocking the synthesis of Thyroxine (T4) and Triiodothyronine (T3).
- Graves’ Disease Management: It is the preferred agent for inducing long-term remission in Graves’ disease and preparing patients for thyroidectomy or radioiodine therapy.
- Predictable Titration: Our tablets allow for precise dosage adjustments during the “Block and Replace” or “Titration” regimens, ensuring the stabilization of the Hypothalamic-Pituitary-Thyroid axis.
Technical & Manufacturing Specifications
Formulated for absolute dosage accuracy and protection against cross-contamination.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Carbimazole BP / USP / IP |
| Dosage Form | Uncoated / Film-Coated Tablets |
| Available Strengths | 5 mg, 10 mg, 20 mg |
| HS Code | 3004.39.19 (Other Hormones) / 2933.29.00 |
| Packaging | Alu-Alu Blister or Amber Glass (To prevent moisture-induced degradation) |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- Dedicated Hormone Block: To ensure zero cross-contamination, Carbimazole is produced in segregated HVAC zones with dedicated equipment, adhering to the highest international safety standards for potent active ingredients.
- Content Uniformity: We utilize validated high-shear granulation to ensure that every 5mg or 10mg tablet contains the exact dose required for sensitive endocrine titration.
- Stability Validation: Validated for Climatic Zone IVb (40°C / 75% RH). Our specialized formulation ensures that the prodrug remains stable and does not prematurely convert to methimazole during storage.
Therapeutic Indications & Clinical Symptoms
- Hyperthyroidism: Primary management of overactive thyroid function.
- Graves’ Disease: Treatment of autoimmune-driven thyrotoxicosis.
- Pre-Operative Preparation: Stabilizing thyroid levels prior to partial or total thyroidectomy.
- Thyroid Storm: Adjunctive use in the emergency management of thyrotoxic crisis.
Dosage & Administration
- Initial Dose: Typically 15 mg to 40 mg daily, depending on the severity of thyrotoxicosis.
- Maintenance Dose: Gradually reduced to 5 mg to 15 mg daily once euthyroid state is achieved.
- Safety Note: Patients must be monitored for signs of agranulocytosis (sore throat, fever, or mouth ulcers). Use with caution in pregnancy (Propylthiouracil is often preferred in the first trimester).
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to Endocrinology Specialty Centers and Ministry of Health Tenders. We offer Third Party Manufacturing for Carbimazole with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, UAE, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
Commercial Inquiries
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
