Description

Cetirizine Hydrochloride Tablets

Healthy Inc is a specialized global supplier and exporter of leading “Second-Generation” antihistamines. We provide high-purity Cetirizine Hydrochloride Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Gold Standard” Anti-Allergic is a top export to retail pharmacy chains, government health tenders, and private clinics in Africa, LATAM, and Southeast Asia, recognized worldwide as the most versatile and effective agent for the rapid relief of seasonal allergies and chronic hives.

[Image of Cetirizine mechanism of action blocking H1 histamine receptors]

Product Overview

This formulation contains Cetirizine Hydrochloride, a piperazine derivative and metabolite of hydroxyzine.

The “Rapid Relief” Specialist:

• Mechanism: Cetirizine works by competitively antagonizing peripheral Histamine H1-receptors on effector cells. By blocking histamine (the chemical released during allergic reactions), it stops symptoms like itching, sneezing, and runny nose.
• Low CNS Penetration: Unlike first-generation antihistamines (like Chlorpheniramine), Cetirizine is a “Zwitterion” (polar molecule). This makes it difficult for the drug to cross the Blood-Brain Barrier, significantly reducing sedation and drowsiness compared to older drugs.
• Anti-Inflammatory: Beyond blocking histamine, it inhibits the migration of eosinophils (inflammatory cells) to the site of the allergy, providing a secondary anti-inflammatory benefit in late-phase allergic reactions.
• Speed & Duration: Onset of action is within 20–60 minutes, and the effect lasts for 24 hours, allowing for convenient once-daily dosing.

Product Composition & Strength

We supply this product as Film Coated Tablets (White/scored). The tablets are scored to facilitate dose splitting for pediatric use.

*Pack Sizes: Blister packs of 10s (Box of 10×10), 30s, 100s, or Bulk HDPE Jars of 1000s (Dispensing Packs).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Taste Masking: Cetirizine HCl has a very bitter metallic taste. We utilize a specialized polymer film coating (Opadry) that dissolves rapidly in the stomach but remains intact in the mouth, ensuring patient compliance, especially in children.
• Dissolution Profile: Our formulation is engineered to release >80% of the drug within 15 minutes, ensuring the promised “fast onset” of allergy relief.

Therapeutic Indications (Human Use)

Indicated for the symptomatic relief of allergic conditions:

• Seasonal Allergic Rhinitis (Hay Fever): Sneezing, runny nose, itchy nose/throat/eyes.
• Perennial Allergic Rhinitis: Year-round allergies (dust mites, pet dander).
• Chronic Idiopathic Urticaria: Relief of itching and reduction in the number and size of hives.

Dosage & Administration

Recommended Dosage (OTC / Physician):

• Route: Oral.
• Adults & Children (> 12 years): 10 mg (1 tablet) once daily.
• Children (6 to 12 years): 5 mg (1/2 tablet) twice daily OR 10 mg once daily.
• Children (2 to 6 years): 2.5 mg (1/4 tablet or syrup) twice daily.
• Timing: Can be taken with or without food. Taking it at night is often recommended if mild drowsiness occurs.

Safety Warnings:

• Sedation: Although “non-sedating,” about 10-14% of patients may experience drowsiness. Caution should be used when driving or operating machinery.
• Alcohol Interaction: Can potentiate the CNS depressant effects of alcohol and sedatives. Avoid concurrent use.
• Renal Impair