Description
Chlorpromazine Hydrochloride Tablets (25mg / 50mg / 100mg)
Healthy Inc is a specialized global supplier and exporter of foundational neuroleptics and anti-emetics. We provide high-stability Chlorpromazine Hydrochloride Tablets, sourced from WHO–GMP certified solid dosage facilities. As the prototype of the first-generation antipsychotics (FGAs), this medication remains a vital export to psychiatric institutions, emergency departments, and government mental health programs in Africa, LATAM, and Southeast Asia.
Product Overview
This formulation contains Chlorpromazine Hydrochloride, a phenothiazine derivative that serves as a multi-receptor antagonist in the central nervous system.
The “Classical Neuroleptic” Specialist:
- Mechanism of Action: Chlorpromazine primarily works by blocking Postsynaptic Dopamine D2 receptors in the mesolimbic pathway of the brain, effectively reducing positive symptoms of psychosis (hallucinations and delusions). It also possesses significant antagonistic activity at serotonin (5-HT), adrenergic (alpha-1), histaminergic (H1), and cholinergic (muscarinic) receptors.
- Anti-Emetic Action: It inhibits the medullary chemoreceptor trigger zone (CTZ), making it highly effective for treating severe nausea, vomiting, and intractable hiccups.
- Sedative Properties: Due to its strong H1 and Alpha-1 blockade, it provides profound sedation, which is clinically useful in managing acute psychomotor agitation and manic episodes.
Product Composition & Strength
We supply this product as Film Coated Tablets. The coating is critical to protect the active ingredient from light-induced oxidation and to prevent contact dermatitis for healthcare providers handling the medication.
| Active Ingredient | Strength (Standard) | Therapeutic Role | |
|---|---|---|---|
| Chlorpromazine HCl BP/USP | 25 mg | Nausea / Pediatric / Mild Sedation | |
| Chlorpromazine HCl BP/USP | 100 mg | Acute Psychosis / Schizophrenia | |
| Excipients | Q.S. | Lactose / Starch / Titanium Dioxide | Opaque Coating Agent |
*Pack Sizes: Blister packs of 10s (Box of 10×10) or Bulk HDPE Jars of 1000s for institutional use.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Medicaments – Other) |
| Dosage Form | Tablet (Film Coated) |
| Packaging | PVC-Alu Blister or Opaque Alu-Alu (Light Sensitive) |
| Storage | Store below 25°C. Protect from Light. Tablets may discolor if exposed to UV. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Photoprotection Technology: Chlorpromazine is highly photosensitive. We utilize Opaque Coating Systems containing Titanium Dioxide to provide a complete light barrier, preventing the formation of toxic photo-degradation products.
- Bioavailability Optimization: Despite being a classical molecule, we maintain strict micronization standards to ensure consistent dissolution rates, providing predictable plasma levels for psychiatric stability.
Therapeutic Indications (Human Use)
Indicated for the management of various psychiatric and medical conditions:
- Schizophrenia: Management of manifestations of psychotic disorders.
- Manic-Depressive Illness: Treatment of acute manic phases.
- Severe Nausea & Vomiting: Effective anti-emetic in surgical and oncological settings.
- Intractable Hiccups: Often the treatment of choice for chronic hiccup relief.
- Porphyria: Management of acute intermittent porphyria.
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Psychosis (Adults): 10 mg to 25 mg TID, gradually increasing until symptoms are controlled (Maintenance 200 mg – 800 mg daily).
- Nausea & Vomiting: 10 mg to 25 mg every 4 to 6 hours as needed.
- Hiccups: 25 mg to 50 mg TID or QID.
Safety Warnings:
- Extrapyramidal Symptoms (EPS): Risk of tardive dyskinesia, dystonia, and parkinsonism. Monitor patients closely.
- Neuroleptic Malignant Syndrome (NMS): Potentially fatal reaction; monitor for high fever, muscle rigidity, and altered mental status.
- Postural Hypotension: Common during the first few days of treatment; patients should rise slowly.
- Photosensitivity: Advise patients to avoid excessive sun exposure to prevent severe sunburn and skin pigmentation.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
