Description
Chlorpromazine Hydrochloride Tablets (25 mg / 50 mg / 100 mg)
Healthy Inc is a premier global supplier of high-precision neuropsychiatric therapies. We provide premium Chlorpromazine Hydrochloride Tablets, manufactured in WHO–GMP certified specialized psychotropic formulation units. As a foundational dopamine antagonist used in the management of acute and chronic psychoses, this product is a vital export for mental health institutes, correctional facilities, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the CIS region.
Product Overview
Chlorpromazine is a propylamino derivative of phenothiazine and remains the gold standard prototype for typical antipsychotics. It is specifically engineered to provide potent sedative and antipsychotic effects by modulating multiple neurotransmitter systems, primarily in the subcortical levels of the brain.
The “Multimodal Neuroleptic” Specialist:
- Mechanism of Action: Chlorpromazine primarily acts as an antagonist at Postsynaptic Dopamine D2 receptors in the mesolimbic and medullary chemoreceptor trigger zone. This action reduces psychotic symptoms and provides a powerful anti-emetic effect. It also possesses significant antagonistic activity at serotonin (5-HT), adrenergic (alpha-1), and histaminergic (H1) receptors.
- Broad Clinical Utility: Beyond schizophrenia, Chlorpromazine is uniquely indicated for the management of intractable hiccups and as a pre-operative sedative to alleviate apprehension.
- Effective Sedation: Its high affinity for H1 and alpha-1 receptors makes it exceptionally effective in controlling acute agitation and violent behavior in psychiatric emergencies.
Technical & Manufacturing Specifications
Formulated for absolute dose uniformity and protection against light-induced degradation.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Chlorpromazine Hydrochloride BP / USP / IP |
| Dosage Form | Film-Coated Tablets |
| Available Strengths | 10 mg, 25 mg, 50 mg, 100 mg, 200 mg |
| HS Code | 3004.90.79 (Psychotropics) / 2934.30.00 |
| Packaging | Amber Glass Vials or Alu-Alu Blisters (Critical for light protection) |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified psychotropic blocks.
- Photostability Engineering: Chlorpromazine is highly sensitive to light (photolabile). Our manufacturing process utilizes opaque film coatings and light-resistant packaging to prevent the formation of inactive degradants, ensuring therapeutic potency for 36 months.
- Containment Excellence: Manufactured in high-containment suites (HAPI) to prevent cross-contamination, ensuring that our neuropsychiatric products maintain the highest safety profile for chronic psychiatric patients.
- Bioavailability Consistency: Every batch undergoes rigorous dissolution testing to ensure the hydrochloride salt is released at a rate that provides predictable plasma concentrations, minimizing the risk of extrapyramidal side effects.
Therapeutic Indications & Clinical Symptoms
- Schizophrenia & Psychosis: Management of manifestations of psychotic disorders.
- Acute Agitation: Control of manic phases in bipolar disorder and aggressive behavior.
- Intractable Hiccups: A specialized indication where Chlorpromazine is the treatment of choice.
- Nausea & Vomiting: Short-term management of severe nausea and vomiting.
- Porphyria: Adjunctive treatment in the management of acute intermittent porphyria.
Dosage & Administration
- Adult Dosage: Highly variable, typically starting from 25 mg to 75 mg daily in divided doses, titrated up to 400 mg or higher in severe chronic cases.
- Administration: Should be taken with water. Can be taken with food to minimize gastric irritation.
- Safety Note: May cause Tardive Dyskinesia and orthostatic hypotension. Patients should be monitored for “Neuroleptic Malignant Syndrome” (NMS). Use with caution in hot climates due to interference with temperature regulation.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to Mental Health Trusts and Ministry of Health Tenders. We offer Third Party Manufacturing for Chlorpromazine with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, Uzbekistan, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
Commercial Inquiries
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
