Description
Ergometrine Maleate Tablets
Healthy Inc is a specialized global supplier and exporter of life-saving maternal health pharmaceuticals. We provide high-stability Ergometrine Maleate Tablets, sourced from WHO–GMP certified solid dosage facilities. This critical “Uterine Tonic” is a top export to maternity wards, government health ministries, and NGO birth programs in Africa, LATAM, and Southeast Asia, serving as a frontline defense against Postpartum Hemorrhage (PPH) caused by uterine atony.
Product Overview
This formulation contains Ergometrine Maleate (also known as Ergonovine), a water-soluble ergot alkaloid.
The “Life-Saving Ligature” Specialist:
- Mechanism: Ergometrine acts directly on the uterine smooth muscle (myometrium) via 5-HT2 and alpha-adrenergic receptors. It increases the tone, rate, and amplitude of rhythmic contractions.
- “Living Ligatures”: At therapeutic doses, it induces a sustained, tetanic contraction of the uterus. This mechanical compression clamps down on the spiral arteries at the placental site, effectively stopping bleeding after childbirth.
- Oral Advantage: While Oxytocin requires injection and cold chain, Ergometrine tablets offer a viable oral option for maintaining uterine tone in low-resource settings or for subinvolution therapy after hospital discharge.
- Speed: Oral administration produces a uterine response within 5 to 10 minutes.
Product Composition & Strength
We supply this product as Sugar Coated or Film Coated Tablets. The coating is critical to protect the active ingredient from oxidation and light.
| Active Ingredient | Strength (Standard) | Primary Role |
|---|---|---|
| Ergometrine Maleate USP/BP | 0.2 mg (200 mcg) | PPH Prevention / Subinvolution |
| Ergometrine Maleate USP/BP | 0.5 mg (500 mcg) | High Potency (Specific Mkts) |
| Excipients | Q.S. | Tartaric Acid (Stabilizer) |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 20s, 100s, or Bulk HDPE Jars (Institutional Packs).
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Tablet (Coated) |
| Packaging | Amber Glass Bottle or Alu-Alu Blister (Strict Light Protection) |
| Storage | Store below 25°C (Ideally 2-8°C for long term). Protect from Light. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Stability Engineering: Ergometrine is notoriously unstable; it degrades rapidly upon exposure to light and heat, turning dark and losing potency. We utilize Amber Glass packaging or Cold-Form Alu-Alu blisters and manufacture under low-actinic light conditions to ensure the product reaching the patient is fully potent.
- Maleate Salt: We use the Maleate salt form which offers the best balance of solubility and stability for oral formulations.
Therapeutic Indications (Human Use)
Indicated for obstetric emergencies and recovery:
- Postpartum Hemorrhage (PPH): Prevention and treatment of PPH due to uterine atony (failure of the uterus to contract).
- Subinvolution: Treatment of imperfect closure of the uterus (slow return to normal size) after childbirth.
- Post-Abortion: Control of hemorrhage following abortion or miscarriage.
Dosage & Administration
Recommended Dosage (Strictly as per Obstetrician/Midwife):
- Route: Oral.
- PPH Prevention/Treatment: 0.2 mg to 0.4 mg (1 or 2 tablets) taken 2 to 4 times daily.
- Duration: Usually limited to 48 hours. Long-term use is not recommended due to risk of ergotism.
- Timing: Typically administered *after* the delivery of the placenta to avoid trapping the placenta inside the uterus.
Safety Warnings:
- Hypertension (Contraindication): Ergometrine causes vasoconstriction and can dangerously raise blood pressure. It is strictly contraindicated in patients with Pre-eclampsia, Eclampsia, or chronic hypertension.
- Sepsis: Use with caution in cases of sepsis (may increase sensitivity to gangrene).
- Lactation: Excreted in breast milk and may suppress lactation. Use only if necessary.
- Cramping: Strong uterine cramps are the expected therapeutic effect, not a side effect, but can be painful.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
