Description
Esomeprazole Magnesium Tablets
Healthy Inc is a specialized global supplier and exporter of advanced acid-suppressant therapies. We provide high-purity Esomeprazole Magnesium Delayed-Release Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Superior Isomer” PPI is a top export to gastroenterology centers, pharmacy chains, and government health formularies in Africa, LATAM, and Southeast Asia, recognized as the most effective agent for healing erosive esophagitis and controlling severe acid reflux.
[Image of Esomeprazole mechanism of action irreversible inhibition of proton pump]
Product Overview
This formulation contains Esomeprazole, the S-isomer of Omeprazole.
The “Acid Control” Specialist:
- Isomeric Advantage: Esomeprazole is the single S-enantiomer of Omeprazole. Because the body metabolizes the S-form more slowly than the R-form, Esomeprazole achieves higher plasma levels and sustains acid suppression longer than standard Omeprazole.
- Mechanism: It is a Proton Pump Inhibitor (PPI). It accumulates in the acidic tubules of the parietal cells in the stomach lining, where it is converted into its active form. It then irreversibly binds to and inhibits the H+/K+ ATPase enzyme (the “proton pump”), stopping the final step of acid production.
- Healing Power: Clinical studies confirm it offers higher healing rates for erosive esophagitis compared to other PPIs.
- H. Pylori Eradication: A key component of “Triple Therapy” (with antibiotics) for curing peptic ulcers caused by bacteria.
Product Composition & Strength
We supply this product as Gastro-Resistant (Enteric Coated) Tablets. The drug is acid-labile and must pass through the stomach intact to be absorbed in the intestine.
| Active Ingredient | Strength (Standard) | Role |
|---|---|---|
| Esomeprazole Magnesium Trihydrate USP/BP | 20 mg | Maintenance / Mild GERD |
| Esomeprazole Magnesium Trihydrate USP/BP | 40 mg | Erosive Esophagitis / Zollinger-Ellison |
| Excipients | Q.S. | Enteric Polymers (Methacrylic Acid) |
*Pack Sizes: Alu-Alu Blister packs of 10s (Box of 10×10), 14s, 28s, or Bulk HDPE Jars.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Delayed-Release Tablet |
| Packaging | Alu-Alu Blister (Highly Moisture Sensitive) |
| Storage | Store below 25°C. Strictly Protect from Moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Enteric Coating Integrity: Esomeprazole is rapidly destroyed by stomach acid. Our tablets utilize advanced Enteric Coating technology (often using MUPS – Multiple Unit Pellet System or standard coating) that ensures the tablet does not disintegrate at pH 1.2 (Stomach) but dissolves rapidly at pH 6.8 (Intestine) for maximum absorption.
- Stability: The Magnesium salt form is used to enhance stability, but it remains sensitive to moisture. We use Cold Form Alu-Alu packaging to guarantee a 24-month shelf life in tropical zones.
Therapeutic Indications (Human Use)
Indicated for the treatment of acid-related disorders:
- GERD (Gastroesophageal Reflux Disease): Treatment of heartburn and other symptoms associated with GERD.
- Erosive Esophagitis: Healing of damage to the esophagus caused by stomach acid.
- Zollinger-Ellison Syndrome: Pathological hypersecretory conditions requiring long-term, high-dose acid suppression.
- NSAID Prophylaxis: Prevention of gastric ulcers in patients taking continuous NSAID therapy (like Diclofenac/Ibuprofen).
Dosage & Administration
Recommended Dosage (Strictly as per Gastroenterologist):
- Route: Oral.
- Healing of Erosive Esophagitis: 40 mg once daily for 4 to 8 weeks.
- Maintenance / Symptomatic GERD: 20 mg once daily.
- H. Pylori Eradication: 40 mg once daily for 10 days (combined with Amoxicillin and Clarithromycin).
- Timing: Best taken at least one hour before a meal (usually breakfast). Food decreases absorption by up to 50%.
- Swallowing: Swallow whole. Do not chew or crush (this destroys the enteric coating).
Safety Warnings:
- Long-Term Risks: Prolonged use (>1 year) may increase the risk of bone fractures (osteoporosis), Vitamin B12 deficiency, and low magnesium levels (Hypomagnesemia).
- C. difficile: PPIs can slightly increase the risk of *Clostridium difficile*-associated diarrhea.
- Drug Interactions: Significantly reduces the activation of Clopidogrel (Plavix), reducing its heart-protective effect. Avoid concurrent use if possible.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
