Description
Gentamicin Injection (Human Use)
Healthy Inc is a specialized global supplier and exporter of potent aminoglycoside antibiotics. We provide high-purity Gentamicin Injection, sourced from WHO–GMP certified sterile facilities. This “Gram-Negative Warrior” is a top export to government hospitals, renal care units, and critical care departments in Africa, LATAM, and Southeast Asia, serving as the frontline defense against severe bacterial sepsis and resistant urinary tract infections.
Product Overview
This formulation contains Gentamicin Sulphate, a broad-spectrum aminoglycoside antibiotic derived from Micromonospora purpurea.
The “Gram-Negative” Specialist:
- Bactericidal Action: Irreversibly binds to the bacterial 30S ribosomal subunit, blocking protein synthesis and causing rapid bacterial cell death.
- Aerobic Powerhouse: Exceptionally effective against aerobic Gram-negative bacilli, including Pseudomonas aeruginosa, E. coli, Proteus, Klebsiella, and Serratia.
- Synergy: Often combined with Beta-lactams (like Ampicillin or Ceftriaxone) to treat Endocarditis, creating a synergistic effect that penetrates bacterial walls more effectively.
- Post-Antibiotic Effect (PAE): Continues to suppress bacterial growth even after blood levels have dropped below the Minimum Inhibitory Concentration (MIC), allowing for once-daily dosing protocols.
Product Composition & Strength
We supply this sterile injection in clear glass vials or ampoules.
| Active Ingredient | Strength (Standard) | Concentration | Role |
|---|---|---|---|
| Gentamicin Sulphate IP/BP/USP | 80 mg / 2 mL | 40 mg / mL | Antibacterial Agent |
| (Pediatric Strength) | 20 mg / 2 mL | 10 mg / mL | Antibacterial Agent |
| Methylparaben / Propylparaben | Q.S. | — | Preservatives |
| Water for Injection | Q.S. | — | Vehicle |
*Pack Sizes: 2ml Ampoules (Tray Pack) or 10ml/30ml Multi-dose Vials.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.20.99 (Medicaments containing other antibiotics) |
| Dosage Form | Sterile Liquid Injection (IM / IV Infusion) |
| Packaging | Clear Glass Ampoule (Type I) or Vial |
| Storage | Store below 25°C. Do not freeze. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Potency Assurance: Aminoglycosides must be dosed precisely to avoid toxicity. Our manufacturing process uses high-precision filling lines to ensure exact dosage in every ampoule.
- Sulphate Stability: Formulated with stabilizers (disodium edetate/sodium bisulfite) to prevent discoloration (oxidation) during shelf life.
Therapeutic Indications (Human Use)
Indicated for serious infections caused by susceptible bacteria:
- Systemic Sepsis: Septicemia caused by Gram-negative organisms.
- Urinary Tract Infections: Complicated and recurrent UTIs (Pyelonephritis).
- Respiratory Tract: Pneumonia in hospitalized patients.
- Infective Endocarditis: Used (with Penicillin) for Enterococcal endocarditis.
- Skin & Soft Tissue: Infected burns, wounds, and skin grafts.
- Meningitis: Used intrathecally or IV for Gram-negative meningitis.
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Intramuscular (IM) or Intravenous (IV) Infusion (over 30-60 mins).
- Adults: 3 mg to 5 mg per kg body weight daily. (Administered as 80 mg every 8 hours OR a single daily dose of 5-7 mg/kg).
- Pediatrics: 2.0 to 2.5 mg/kg every 8 hours.
- Renal Impairment: CRITICAL: Dosage interval must be extended based on Creatinine Clearance to prevent kidney damage.
Safety Warnings:
- Ototoxicity: Can cause permanent hearing loss or vestibular damage (dizziness/balance loss). Risk increases with high doses or prolonged use (>7 days).
- Nephrotoxicity: Can cause kidney damage. Monitor serum creatinine and BUN levels regularly.
- Neuromuscular Blockade: Can cause respiratory paralysis if given too rapidly or with muscle relaxants (anesthesia).
- Hydration: Patients must be well-hydrated during treatment to protect the kidneys.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
