Description
Glimepiride Tablets
Healthy Inc is a specialized global supplier and exporter of advanced “Third-Generation” anti-diabetic agents. We provide high-purity Glimepiride Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Dual-Mode” Sulfonylurea is a top export to diabetic care clinics, government procurement agencies, and retail pharmacy chains in Africa, LATAM, and Southeast Asia, serving as the modern standard for Type 2 diabetes management due to its insulin-sparing properties and lower risk of hypoglycemia.
Product Overview
This formulation contains Glimepiride, a third-generation sulfonylurea.
The “Insulin Sparing” Specialist:
- Dual Mechanism:
- Pancreatic (Secretion): Like older sulfonylureas, it stimulates beta cells to release insulin by blocking ATP-sensitive potassium channels. However, it binds to a different protein subunit (65-kDa) and dissociates faster, reducing the risk of “exhausting” the pancreas.
- Extrapancreatic (Sensitization): Uniquely, Glimepiride increases the number of active glucose transporters (GLUT4) in muscle and fat cells. This improves the body’s sensitivity to insulin, meaning less insulin is needed to achieve the same blood sugar reduction (“Insulin Sparing Effect”).
- Cardiovascular Safety: It has less interference with the mechanism of “ischemic preconditioning” in the heart compared to Glibenclamide, making it safer for patients with heart disease.
- Hypoglycemia Risk: Because it dissociates rapidly from the receptor, insulin secretion drops quickly once blood sugar normalizes, significantly lowering the risk of dangerous low blood sugar events.
Product Composition & Strength
We supply this product as Uncoated Tablets (often color-coded by strength). This allows for precise titration from very low doses.
| Active Ingredient | Strength (Standard) | Color Code (Typical) | Role |
|---|---|---|---|
| Glimepiride USP/BP/IP | 1 mg | Pink | Initial Dose |
| Glimepiride USP/BP/IP | 2 mg | Green | Titration Step 1 |
| Glimepiride USP/BP/IP | 3 mg | Yellow | Titration Step 2 |
| Glimepiride USP/BP/IP | 4 mg | Blue | Maintenance / High Dose |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 15s, 30s, or Bulk HDPE Jars of 1000s/5000s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Tablet (Oral) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister |
| Storage | Store below 25°C. Protect from moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Micronization: Glimepiride is practically insoluble in water (Class II drug). We use micronized API to ensure rapid and consistent bioavailability.
- Content Uniformity (Critical): Since the lowest dose is only 1 mg, ensuring this tiny amount is evenly distributed in every tablet is a manufacturing challenge. We use advanced geometric blending and direct compression techniques to guarantee no tablet is sub-potent.
Therapeutic Indications (Human Use)
Indicated for the treatment of Type 2 Diabetes Mellitus:
- Adjunct to Diet & Exercise: When lifestyle changes alone fail to control hyperglycemia.
- Combination Therapy: Highly effective when combined with Metformin or Insulin.
Dosage & Administration
Recommended Dosage (Strictly as per Endocrinologist):
- Route: Oral.
- Initial Dose: 1 mg or 2 mg once daily.
- Titration: Increase in increments of 1 mg or 2 mg at 1-2 week intervals based on blood glucose response.
- Maintenance Dose: Usually 1 mg to 4 mg daily.
- Maximum Dose: 6 mg to 8 mg daily.
- Timing: MUST be taken with breakfast or the first main meal. Skipping the meal can induce hypoglycemia.
Safety Warnings:
- Hypoglycemia: Although safer than older drugs, low blood sugar can still occur, especially in elderly patients or those with kidney issues.
- Weight Gain: Some weight gain may occur, though typically less than with Glibenclamide.
- Sulfa Allergy: Use with caution in patients allergic to sulfonamides.
- Hemolytic Anemia: Can occur in patients with G6PD deficiency.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
