Description
Mebeverine Hydrochloride Tablets (135 mg / 200 mg SR)
Healthy Inc is a premier global supplier of high-stability gastrointestinal therapies. We provide premium Mebeverine Hydrochloride Tablets, available in standard and Sustained-Release (SR) formulations, manufactured in WHO–GMP certified specialized solid dosage units. As a frontline treatment for Irritable Bowel Syndrome (IBS), this product is a cornerstone export for gastroenterology clinics, abdominal pain management centers, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the Middle East.
Product Overview
Mebeverine is a musculotropic antispasmodic agent with a direct effect on the smooth muscle of the gastrointestinal tract. It is specifically engineered to relieve abdominal cramps and spasms without the systemic side effects typically associated with anticholinergic medications, such as dry mouth or blurred vision.
The “IBS Comfort” Specialist:
- Mechanism of Action: Mebeverine acts directly on the smooth muscle of the colon. It works by reducing the permeability of ion channels to sodium, and by blocking the replenishment of intracellular calcium stores, thereby preventing the excessive contractions that lead to pain and spasm.
- Non-Anticholinergic Profile: Unlike hyoscine or dicyclomine, Mebeverine does not block acetylcholine receptors. This makes it a safer and better-tolerated option for long-term use in patients with glaucoma or prostatic hypertrophy.
- Sustained Relief: Our 200 mg SR formulation utilizes advanced matrix technology to provide 12-hour symptomatic relief, ensuring consistent bowel regulation and improved patient compliance.
Technical & Manufacturing Specifications
Formulated for precise release kinetics and molecular stability in tropical climates.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Mebeverine Hydrochloride BP / USP / IP |
| Dosage Form | Film-Coated Tablets / Sustained-Release Capsules |
| Available Strengths | 135 mg (IR), 200 mg (SR) |
| HS Code | 3004.90.99 (Medicaments) / 2922.49.90 |
| Packaging | Alu-Alu Blister (Crucial for moisture exclusion and stability) |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- SR Matrix Engineering: Our 200 mg Sustained-Release tablets are developed using a dual-polymer erosion system that ensures the API is released slowly as the tablet moves through the GI tract, specifically targeting the colon.
- Odor-Masking Coating: Mebeverine API can have a distinct chemical profile; we utilize a neutralizing film coating to ensure patient acceptability and swallowability.
- Stability Validation: Validated for Climatic Zone IVb (40°C / 75% RH). Our formulation maintains structural integrity and release profiles even in the demanding environments of our export markets.
Therapeutic Indications & Clinical Symptoms
- Irritable Bowel Syndrome (IBS): Symptomatic treatment of abdominal pain, cramps, persistent diarrhea, and flatulence.
- Chronic Irritable Colon: Long-term management of spastic colon and mucous colitis.
- Gastrointestinal Spasm: Relief of secondary spasms caused by organic diseases.
Dosage & Administration
- 135 mg Tablets: One tablet three times daily, preferably 20 minutes before meals.
- 200 mg SR: One capsule/tablet twice daily (morning and evening).
- Administration: Should be swallowed whole with plenty of water. Do not chew or crush SR variants to avoid “dose dumping.”
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to Gastroenterology Centers and Retail Pharmacy Chains. We offer Third Party Manufacturing for Mebeverine with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, UAE, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
Commercial Inquiries
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
