Description

Metronidazole Tablets (200 mg / 250 mg / 400 mg / 500 mg)

Healthy Inc is a premier global supplier of high-efficacy anti-infective therapies. We provide premium Metronidazole Tablets, manufactured in WHO–GMP certified specialized antibiotic production blocks. As a cornerstone of anaerobic and antiprotozoal therapy, this product is a vital export for gastroenterology clinics, dental centers, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the CIS region.

Product Overview

Metronidazole is a synthetic nitroimidazole derivative with potent antibacterial and antiprotozoal activity. It is specifically engineered to target organisms that thrive in low-oxygen environments, making it indispensable for deep-seated infections and intestinal parasitology.

The “Anaerobic Pathogen” Specialist:

• Mechanism of Action: Metronidazole acts as a prodrug. Within anaerobic organisms, the nitro group is reduced to unstable intermediate nitro radical anions. these intermediates interact with bacterial DNA, causing loss of helical structure and strand breakage, effectively inhibiting nucleic acid synthesis and causing cell death.
• Broad Therapeutic Spectrum: It is highly effective against anaerobic bacteria (such as Bacteroides fragilis and Clostridium difficile) and protozoa including Entamoeba histolytica, Giardia lamblia, and Trichomonas vaginalis.
• Excellent Bioavailability: Metronidazole is rapidly and almost completely absorbed after oral administration, with high concentrations achieved in most body tissues and fluids, including the CSF, saliva, and breast milk.

Technical & Manufacturing Specifications

Formulated for rapid disintegration and absolute chemical purity.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.

• Stability Validation: Validated for Zone IVb climates (40°C / 75% RH). Our tablets utilize specialized film-coating to mask the characteristic bitter metallic taste and to protect the core from environmental humidity in tropical export markets.
• Dissolution Precision: We ensure 100% batch-to-batch consistency in disintegration and dissolution rates (typically >85% in 30 minutes), ensuring rapid therapeutic onset for acute GI and dental infections.
• Impurity Profiling: Using High-Performance Liquid Chromatography (HPLC), we monitor for 2-methyl-5-nitroimidazole and other process-related impurities to meet stringent international safety standards.

Therapeutic Indications & Clinical Symptoms

• Amoebiasis & Giardiasis: Treatment of intestinal and extra-intestinal (liver abscess) protozoal infections.
• Trichomoniasis: Effective treatment for symptomatic and asymptomatic urogenital infections.
• Anaerobic Infections: Management of intra-abdominal, gynecological, and respiratory tract infections caused by susceptible anaerobes.
• Dental Infections: Treatment of acute ulcerative gingivitis and acute pericoronitis.
• H. pylori Eradication: Used as part of triple-therapy regimens for peptic ulcer disease.

Dosage & Administration

• Administration: Tablets should be taken during or after meals to minimize gastrointestinal distress.
• Standard Course: Varies by indication; typically 400 mg to 500 mg every 8 to 12 hours for 5–10 days.
• Safety Note: Disulfiram-like reaction: Patients must strictly avoid alcohol during and for 48 hours after treatment. Monitor for peripheral neuropathy in long-term therapy.

Global Export & Contract Manufacturing Services

Healthy Inc is a verified Antibiotic and Antiprotozoal Exporter in Mumbai, catering to Gastroenterology Centers and Ministry of Health Tenders. We offer Third Party Manufacturing for Metronidazole with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, Uzbekistan, and the Philippines, providing WHO-GMP quality at competitive B2B prices.

Commercial Inquiries

WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in