Description
Nalidixic Acid Tablets (500 mg)
Healthy Inc is a specialized global supplier and exporter of first-generation quinolone antibiotics. We provide high-stability Nalidixic Acid 500 mg Tablets, sourced from WHO–GMP certified solid dosage facilities. This targeted antibacterial agent is a top export to urology clinics, diagnostic centers, and government health programs in Africa, LATAM, and Southeast Asia, serving as a primary treatment for acute and chronic urinary tract infections (UTIs).
Product Overview
This formulation contains Nalidixic Acid, a synthetic quinolone that reaches high concentrations in the urine, making it exceptionally effective against Gram-negative uropathogens.
The “Urinary Tract” Specialist:
- Mechanism of Action: Nalidixic Acid works by inhibiting the A-subunit of bacterial DNA gyrase (Topoisomerase II). This enzyme is essential for the supercoiling and replication of bacterial DNA. By blocking this process, the medication prevents bacterial protein synthesis and replication, leading to a bactericidal effect against sensitive organisms.
- Gram-Negative Focus: It is highly active against common urinary pathogens, including Escherichia coli, Proteus species, Klebsiella, and Enterobacter. Because it is rapidly excreted by the kidneys, it maintains peak therapeutic levels within the urinary tract rather than the systemic circulation.
- Resistance Management: While newer fluoroquinolones are broad-spectrum, Nalidixic Acid remains a vital “narrow-spectrum” tool for specific uncomplicated UTIs, helping to preserve stronger antibiotics for systemic infections.
Product Composition & Strength
We supply this product as Uncoated or Film Coated Tablets. The formulation is engineered for rapid disintegration to ensure the active ingredient is quickly processed for renal excretion.
| Active Ingredient | Strength (Standard) | Therapeutic Role | |
|---|---|---|---|
| Nalidixic Acid BP/USP | 500 mg | Quinolone Antibacterial | |
| Excipients | Q.S. | Maize Starch / Gelatin | Binder & Disintegrant |
| Coating (Optional) | Q.S. | HPMC / Titanium Dioxide | Film Coating |
*Pack Sizes: Blister packs of 10s (Box of 10×10) or Bulk HDPE Jars of 500s/1000s for Hospital use.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.20.19 (Antibiotics – Other) |
| Dosage Form | Tablet (Uncoated / Film Coated) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister |
| Storage | Store below 30°C. Protect from light. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Light Barrier Technology: Nalidixic Acid is sensitive to ultraviolet light. Our manufacturing process ensures minimal exposure, and our film-coated variants utilize an opaque barrier to ensure the tablets do not undergo photo-degradation during storage.
- Optimized Renal Clearance: Our R&D team has optimized the particle size of the API to ensure maximum solubility in the urinary pH range, maximizing the antibacterial efficacy per dose.
Therapeutic Indications (Human Use)
Indicated for the treatment of urinary tract infections caused by susceptible Gram-negative bacteria:
- Acute UTIs: Cystitis and urethritis.
- Chronic UTIs: Recurrent urinary infections that have not responded to other narrow-spectrum agents.
- Shigellosis: In some regions, used for the treatment of bacillary dysentery caused by sensitive strains.
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Adults: 1 gram (2 tablets) four times daily for 7 to 14 days.
- Maintenance: For chronic infections, the dose may be reduced to 500 mg four times daily.
- Administration: Best taken 1 hour before meals on an empty stomach to ensure maximum absorption.
Safety Warnings:
- Photosensitivity: WARNING: Patients should avoid direct sunlight. Severe skin reactions can occur if exposed to UV light during treatment.
- CNS Effects: Use with caution in patients with a history of seizures or increased intracranial pressure.
- Cartilage Warning: Like other quinolones, it is generally avoided in young children due to potential effects on weight-bearing joints (unless benefit outweighs risk).
- Hemolytic Anemia: Use with caution in patients with G6PD deficiency.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
