Description
Sodium Valproate & Valproic Acid Tablets (Controlled Release)
Healthy Inc is a specialized global supplier and exporter of broad-spectrum neurological agents. We provide high-quality Sodium Valproate & Valproic Acid Tablets (Controlled Release), sourced from WHO–GMP certified solid dosage facilities. This “Mood Stabilizer & Anticonvulsant” is a top export to psychiatric institutions, epilepsy centers, and government medical stores in Africa, LATAM, and Southeast Asia, serving as a first-line therapy for epilepsy and Bipolar Disorder.
Product Overview
This formulation combines Sodium Valproate and Valproic Acid in a Controlled Release (CR) or Chrono matrix.
The “Broad Spectrum” Neurological Specialist:
- Mechanism of Action: Increases the concentration of GABA (Gamma-Aminobutyric Acid), an inhibitory neurotransmitter in the brain, effectively calming excessive electrical activity.
- Epilepsy Management: Highly effective for multiple seizure types, including generalized tonic-clonic, absence, and myoclonic seizures.
- Mood Stabilization: A gold-standard treatment for acute manic episodes associated with Bipolar Disorder, reducing impulsivity and agitation.
- Migraine Prophylaxis: Often prescribed to reduce the frequency and severity of chronic migraine attacks.
Product Composition & Strength
We supply this product as Controlled Release (CR) / Chrono Tablets to ensure stable blood levels over 24 hours.
| Product Strength | Sodium Valproate | Valproic Acid | Total Valproate |
|---|---|---|---|
| 200 mg CR | 133 mg | 58 mg | ~200 mg |
| 300 mg CR | 200 mg | 87 mg | ~300 mg |
| 500 mg CR | 333 mg | 145 mg | ~500 mg |
| Enteric Coated | 200/500 mg | (Sodium Valproate Only) | Standard Release |
*Pack Sizes: Blister packs of 10s (Box of 10×10) or bulk jars of 100s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Controlled Release Film Coated Tablet (Oral) |
| Packaging | Alu-Alu Blister (Hygroscopic – Moisture Sensitive) |
| Storage | Store below 25°C. Keep highly protected from moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Hygroscopic Control: Sodium Valproate is extremely deliquescent (absorbs moisture from air). We manufacture in low-humidity suites (< 30% RH) and use high-barrier Alu-Alu packaging to prevent the tablets from turning soft or sticky.
- Dissolution Profile: The “CR” technology is rigorously tested to ensure steady drug release, preventing peak-dose side effects (tremors) and end-of-dose seizures.
Therapeutic Indications (Human Use)
Indicated for neurological and psychiatric disorders:
- Epilepsy: Treatment of generalized and partial seizures, including absence seizures (Petit Mal) and tonic-clonic seizures (Grand Mal).
- Bipolar Disorder: Treatment of manic episodes associated with Bipolar I Disorder.
- Migraine: Prophylaxis of migraine headaches (not for acute treatment).
Dosage & Administration
Recommended Dosage (Strictly as per Neurologist/Psychiatrist):
- Route: Oral.
- Epilepsy (Adults): Starting dose 600 mg daily, increasing by 200 mg every 3 days. Maintenance: 1000-2000 mg/day.
- Bipolar Mania: Initial dose 750 mg daily in divided doses.
- Administration: Take with food to reduce nausea. Swallow whole; crushing the CR tablet destroys the sustained-release mechanism.
Safety Warnings:
- Liver Toxicity: Can cause severe hepatotoxicity (liver damage), especially in young children. Regular liver function tests (LFTs) are mandatory.
- Pregnancy (Teratogenicity): Strictly Contraindicated in Pregnancy (unless no alternative exists) due to high risk of birth defects (Spina Bifida).
- Pancreatitis: Rare but life-threatening risk of pancreas inflammation.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
